Tumour Microenvironment in HPV-Related Oropharyngeal Carcinoma

The microenvironment differs between HPV-related and non-HPV orophayrngeal carcinoma

Carcinogenesis. 2018 Feb 9;39(2):170-179.

HPV-negative, but not HPV-positive, oropharyngeal carcinomas induce fibroblasts to support tumour invasion through micro-environmental release of HGF and IL-6.

Bolt R, Foran B, Murdoch C, Lambert DW, Thomas S, Hunter KD.